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amplicon analysis tool  (Inscripta Inc)

 
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    Inscripta Inc amplicon analysis tool
    Amplicon Analysis Tool, supplied by Inscripta Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/amplicon+analysis+tool/us11845932-685-8-7?v=Inscripta+Inc
    Average 90 stars, based on 1 article reviews
    amplicon analysis tool - by Bioz Stars, 2026-06
    90/100 stars

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    Image Search Results


    Alignments of amino acid sequences of MHC class I exon 3 (A) and MHC class II exon 2 (B) in finches and buntings (one sequence shown per species). Dots indicate amino acids identical with the consensus sequence (generated from all available sequence). Positively selected residues are marked with red, while negatively selected residues are marked with blue. Dark and light colours indicate selection supported with both or either Bayesian (FUBAR) and maximum-likelihood (FEL) approaches, respectively (as inferred for non-recombinant sequences only). Residues of the putative peptide-binding region (PBR) of passerine birds (based on the global analysis of selection by Minias et al. 2018) and humans (based on the crystallographic structure of MHC molecules by Saper et al. 1991 and Brown et al. 1993) are indicated with large dots (•) at the top of each alignment. Variation in selection parameter (dN–dS; FUBAR analysis) is shown above the alignments.

    Journal: Heredity

    Article Title: Distinct evolutionary trajectories of MHC class I and class II genes in Old World finches and buntings

    doi: 10.1038/s41437-021-00427-8

    Figure Lengend Snippet: Alignments of amino acid sequences of MHC class I exon 3 (A) and MHC class II exon 2 (B) in finches and buntings (one sequence shown per species). Dots indicate amino acids identical with the consensus sequence (generated from all available sequence). Positively selected residues are marked with red, while negatively selected residues are marked with blue. Dark and light colours indicate selection supported with both or either Bayesian (FUBAR) and maximum-likelihood (FEL) approaches, respectively (as inferred for non-recombinant sequences only). Residues of the putative peptide-binding region (PBR) of passerine birds (based on the global analysis of selection by Minias et al. 2018) and humans (based on the crystallographic structure of MHC molecules by Saper et al. 1991 and Brown et al. 1993) are indicated with large dots (•) at the top of each alignment. Variation in selection parameter (dN–dS; FUBAR analysis) is shown above the alignments.

    Article Snippet: Illumina data processing and allele validation Illumina sequencing data were processed using the Amplicon Sequencing Analysis Tools (AmpliSAT) web server (Sebastian et al. 2016 ) and algorithms implemented therein.

    Techniques: Sequencing, Generated, Selection, Recombinant, Binding Assay